Protein Name VAMP-associated protein 33kDa
Organism Drosophila melanogaster
Gene ID 31349
Gene Symbol

Vap33

UniProt Q9W4N8 (Q9W4N8_DROME), Q7KVX5 (Q7KVX5_DROME)
Relationships Total Number of functionally related compound(s) : 4
Total Number of Articles : 4
Description

VAMP-associated protein 33kDa

Gene Summary

Predicted to enable FFAT motif binding activity. Involved in several processes, including cytoplasmic microtubule organization; defense response to Gram-negative bacterium; and synapse organization. Located in endoplasmic reticulum; extracellular space; and plasma membrane. Is expressed in adult head; adult heart; and organism. Used to study amyotrophic lateral sclerosis; amyotrophic lateral sclerosis type 8; autosomal dominant adult-onset proximal spinal muscular atrophy; motor neuron disease; and neurodegenerative disease. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis; amyotrophic lateral sclerosis type 8; autosomal dominant adult-onset proximal spinal muscular atrophy; and spinal muscular atrophy. Orthologous to human VAPA (VAMP associated protein A) and VAPB (VAMP associated protein B and C). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • VAMP-associated protein 33kDa
  • CG5014-PA
  • CG5014-PB
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Properties