Protein Name solute carrier family 12 member 1 L homeolog
Organism Xenopus laevis
Gene ID 101101701
Gene Symbol

slc12a1.L

UniProt A0A1L8H0K3 (A0A1L8H0K3_XENLA)
Relationships Total Number of functionally related compound(s) : 16
Total Number of Articles : 13
Description

solute carrier family 12 member 1 L homeolog

Gene Summary

Predicted to enable chloride:monoatomic cation symporter activity. Predicted to act upstream of or within potassium ion transport; sodium ion transport; and transmembrane transport. Predicted to be located in plasma membrane. Is expressed in mesenchyme; nervous system; primary germ layer; and urinary system. Human ortholog(s) of this gene implicated in Bartter disease and Bartter disease type 1. Orthologous to human SLC12A1 (solute carrier family 12 member 1). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • solute carrier family 12 member 1
  • NKCC2
  • Na-K-2Cl cotransporter
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Properties