Protein Name complement receptor 2
Organism Mus musculus
Gene ID 12902
Gene Symbol

Cr2

UniProt Q9DC83 (Q9DC83_MOUSE), A0A1B0GS59 (A0A1B0GS59_MOUSE)
Relationships Total Number of functionally related compound(s) : 52
Total Number of Articles : 45
Description

complement receptor 2

Gene Summary

Enables complement receptor activity. Acts upstream of or within with a negative effect on complement activation, alternative pathway. Acts upstream of or within several processes, including cellular response to lipopolysaccharide; immunoglobulin mediated immune response; and skeletal system development. Located in external side of plasma membrane. Human ortholog(s) of this gene implicated in common variable immunodeficiency; nasopharynx carcinoma; and systemic lupus erythematosus. Orthologous to human CR2 (complement C3d receptor 2). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • complement receptor type 2
  • complement C3d receptor
  • complement receptor type 1
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Properties