Protein Name microtubule associated protein RP/EB family member 1
Organism Homo sapiens
Gene ID 22919
Gene Symbol


UniProt Q15691 (MARE1_HUMAN)
Relationships Total Number of functionally related compound(s) : 97
Total Number of Articles : 116

microtubule associated protein RP/EB family member 1

Gene Summary

The protein encoded by this gene was first identified by its binding to the APC protein which is often mutated in familial and sporadic forms of colorectal cancer. This protein localizes to microtubules, especially the growing ends, in interphase cells. During mitosis, the protein is associated with the centrosomes and spindle microtubules. The protein also associates with components of the dynactin complex and the intermediate chain of cytoplasmic dynein. Because of these associations, it is thought that this protein is involved in the regulation of microtubule structures and chromosome stability. This gene is a member of the RP/EB family. [provided by RefSeq, Jul 2008]

  • microtubule-associated protein RP/EB family member 1
  • APC-binding protein EB1
  • adenomatous polyposis coli-binding protein EB1
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