| Protein Name | insulin-like growth factor I receptor |
|---|---|
| Organism | Mus musculus |
| Gene ID | 16001 |
| Gene Symbol | Igf1r |
| UniProt | Q60751 (IGF1R_MOUSE), E9QNX9 (E9QNX9_MOUSE), Q3U1L4 (Q3U1L4_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
236
Total Number of Articles : 304 |
Description |
insulin-like growth factor I receptor |
| Gene Summary |
Enables insulin-like growth factor binding activity and insulin-like growth factor receptor activity. Involved in several processes, including adrenal gland development; insulin-like growth factor receptor signaling pathway; and positive regulation of metabolic process. Acts upstream of or within several processes, including exocrine pancreas development; peptidyl-tyrosine autophosphorylation; and regulation of intracellular signal transduction. Located in T-tubule. Is active in glutamatergic synapse. Is expressed in several structures, including alimentary system; brain; ear; genitourinary system; and limb. Human ortholog(s) of this gene implicated in several diseases, including IgA glomerulonephritis; dementia (multiple); kidney cancer (multiple); liver disease (multiple); and neurodegenerative disease (multiple). Orthologous to human IGF1R (insulin like growth factor 1 receptor). [provided by Alliance of Genome Resources, Jul 2025] |
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