Protein Name Aminolevulinate synthase
Organism Drosophila melanogaster
Gene ID 37815
Gene Symbol

Alas

UniProt O18680 (O18680_DROME)
Relationships Total Number of functionally related compound(s) : 4
Total Number of Articles : 2
Description

Aminolevulinate synthase

Gene Summary

Predicted to enable 5-aminolevulinate synthase activity. Involved in chitin-based cuticle development. Predicted to be located in mitochondrial matrix. Predicted to be active in mitochondrion. Is expressed in Bolwig organ primordium; adult head; embryonic/larval oenocyte; organism; and ring gland. Human ortholog(s) of this gene implicated in cutaneous porphyria; erythropoietic protoporphyria; hemochromatosis; sideroblastic anemia; and sideroblastic anemia 1. Orthologous to human ALAS1 (5'-aminolevulinate synthase 1) and ALAS2 (5'-aminolevulinate synthase 2). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • aminolevulinate synthase
  • Alas-PA
  • Alas/50-Aminolevulinate synthase
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Properties