CPRiL

Protein Name	C-C motif chemokine ligand 26
Organism	Homo sapiens
Gene ID	10344
Gene Symbol	CCL26
UniProt	Q9Y258 (CCL26_HUMAN)
Relationships	Total Number of functionally related compound(s) : 146 Total Number of Articles : 122
Description	C-C motif chemokine ligand 26
Gene Summary	This gene is one of two Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 7. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for normal peripheral blood eosinophils and basophils. This protein also has antimicrobial activity, displaying an antibacterial effect on S. pneumoniae, S. aureus, Non-typeable H. influenzae, and P. aeruginosa. The product of this gene is one of three related chemokines that specifically activate chemokine receptor CCR3. This chemokine may contribute to the eosinophil accumulation in atopic diseases. [provided by RefSeq, Jul 2020]
synonyms	C-C motif chemokine 26 CC chemokine IMAC MIP-4-alpha chemokine (C-C motif) ligand 26 chemokine N1 eotaxin-3 macrophage inflammatory protein 4-alpha small inducible cytokine A26 small inducible cytokine subfamily A (Cys-Cys), member 26 thymic stroma chemokine-1 IMAC MIP-4a MIP-4alpha SCYA26 TSC-1 Click to show/hide the synonyms
Properties