CPRiL

SPANXB1

SPANX family member B1

Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family of cancer/testis-associated genes, which are located in a cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular family member contains an additional 18 nucleotides in its coding region compared to the other family members in the same gene cluster. This family member is also subject to gene copy number variation. Although the protein encoded by this gene contains consensus nuclear localization signals, the major site for subcellular localization of expressed protein is in the cytoplasmic droplets of ejaculated spermatozoa. This protein provides a biochemical marker for studying the unique structures in spermatazoa, while attempting to further define its role in spermatogenesis. [provided by RefSeq, Apr 2014]

• sperm protein associated with the nucleus on the X chromosome B1
• SPANX family member B/F
• SPANX family member F1
SPANX family, member B2
SPANX family, member F2
cancer/testis antigen 11.2
cancer/testis antigen family 11, member 2
nuclear-associated protein SPAN-Xb
nuclear-associated protein SPAN-Xf
sperm protein associated with the nucleus on the X chromosome B/F
sperm protein associated with the nucleus, X chromosome, family member B1
B1
CT11.2
SPANX-B
SPANXB
SPANXB2
SPANXF1
SPANXF2