Protein Name interferon gamma receptor 1
Organism Mus musculus
Gene ID 15979
Gene Symbol

Ifngr1

UniProt P15261 (INGR1_MOUSE)
Relationships Total Number of functionally related compound(s) : 33
Total Number of Articles : 35
Description

interferon gamma receptor 1

Gene Summary

Predicted to enable type II interferon receptor activity. Involved in glial cell activation; negative regulation of amyloid-beta clearance; and positive regulation of macromolecule metabolic process. Acts upstream of or within defense response to virus. Predicted to be located in dendrite and vesicle. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; bone; cerebral cortex; female reproductive system; and liver. Used to study osteoporosis. Human ortholog(s) of this gene implicated in asthma; hepatitis B; immunodeficiency 27A; immunodeficiency 27B; and tuberculosis. Orthologous to human IFNGR1 (interferon gamma receptor 1). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • interferon gamma receptor 1
  • IFN-gamma receptor 1
  • IFN-gamma-R-alpha
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Properties