| Protein Name | lipin 1 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 14245 |
| Gene Symbol | Lpin1 |
| UniProt | Q91ZP3 (LPIN1_MOUSE), A0A1Y7VLN4 (A0A1Y7VLN4_MOUSE), E9QKQ5 (E9QKQ5_MOUSE), A0A5F8MQ53 (A0A5F8MQ53_MOUSE), Q8CD95 (Q8CD95_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
80
Total Number of Articles : 82 |
Description |
lipin 1 |
| Gene Summary |
Enables several functions, including histone deacetylase binding activity; peroxisome proliferator activated receptor binding activity; and phosphatidate phosphatase activity. Involved in several processes, including mitochondrial fission; positive regulation of cold-induced thermogenesis; and triglyceride mobilization. Acts upstream of or within several processes, including actin cytoskeleton reorganization; positive regulation of histone deacetylation; and ruffle organization. Located in endoplasmic reticulum; mitochondrial outer membrane; and nuclear membrane. Part of transcription regulator complex. Is expressed in liver; nervous system; olfactory epithelium; and tooth. Used to study lipodystrophy. Orthologous to human LPIN1 (lipin 1). [provided by Alliance of Genome Resources, Apr 2022] |
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| Properties | |