Protein Name thiamine diphosphate-binding fold (THDP-binding) superfamily protein
Organism Arabidopsis thaliana
Gene ID 839031
Gene Symbol

IAR4

UniProt Q8H1Y0 (ODPA2_ARATH), A0A5S9VTJ7 (A0A5S9VTJ7_ARATH)
Relationships Total Number of functionally related compound(s) : 13
Total Number of Articles : 5
Description

thiamine diphosphate-binding fold (THDP-binding) superfamily protein

Gene Summary

Arabidopsis thaliana pyruvate dehydrogenase E1a-like subunit. 81% identical to a previously characterized Arabidopsis mitochondrial PDH E1a-subunit, At1g59900. Serine 296 phosphorylation of IAR4 has critical function in root hair formation and root development. Changing Ser296 in IAR4 to Ala resulted in a phenotype intermediate between mutant and wild-type, while substitution to Asp was either lethal or caused an extreme dwarf phenotype.

synonyms
  • thiamine diphosphate-binding fold (THDP-binding) superfamily protein
  • AT1G24180
  • F3I6.11
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Properties