Protein Name phosphatidylinositol glycan anchor biosynthesis class M
Organism Homo sapiens
Gene ID 93183
Gene Symbol

PIGM

UniProt Q9H3S5 (PIGM_HUMAN)
Relationships Total Number of functionally related compound(s) : 11
Total Number of Articles : 6
Description

phosphatidylinositol glycan anchor biosynthesis class M

Gene Summary

This gene encodes a transmembrane protein that is located in the endoplasmic reticulum and is involved in GPI-anchor biosynthesis. The glycosylphosphatidylinositol (GPI)-anchor is a glycolipid which contains three mannose molecules in its core backbone. The GPI-anchor is found on many blood cells and serves to anchor proteins to the cell surface. This gene encodes a mannosyltransferase, GPI-MT-I, that transfers the first mannose to GPI on the lumenal side of the endoplasmic reticulum. [provided by RefSeq, Jul 2008]

synonyms
  • GPI alpha-1,4-mannosyltransferase I, catalytic subunit
  • DPM:GlcN-(acyl-)PI mannosyltransferase
  • GPI mannosyltransferase 1
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Properties