Protein Name histidine ammonia-lyase
Organism Homo sapiens
Gene ID 3034
Gene Symbol


UniProt P42357 (HUTH_HUMAN)
Relationships Total Number of functionally related compound(s) : 220
Total Number of Articles : 147

histidine ammonia-lyase

Gene Summary

Histidine ammonia-lyase is a cytosolic enzyme catalyzing the first reaction in histidine catabolism, the nonoxidative deamination of L-histidine to trans-urocanic acid. Histidine ammonia-lyase defects cause histidinemia which is characterized by increased histidine and histamine and decreased urocanic acid in body fluids. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]

  • histidine ammonia-lyase
  • histidase
  • HIS
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