| Protein Name | serine/threonine protein kinase CLA4 |
|---|---|
| Organism | Saccharomyces cerevisiae S288C |
| Gene ID | 855418 |
| Gene Symbol | CLA4 |
| UniProt | P48562 (CLA4_YEAST) |
| Relationships |
Total Number of functionally related compound(s) :
15
Total Number of Articles : 15 |
Description |
serine/threonine protein kinase CLA4 |
| Gene Summary |
Enables protein serine/threonine kinase activity. Involved in several processes, including negative regulation of macromolecule biosynthetic process; negative regulation of sterol import; and positive regulation of protein import into nucleus. Located in cellular bud; fungal-type vacuole; and nucleus. Human ortholog(s) of this gene implicated in breast cancer; ductal carcinoma in situ; non-syndromic X-linked intellectual disability 30; renal cell carcinoma (multiple); and schizophrenia. Orthologous to several human genes including BUB1B-PAK6 (BUB1B-PAK6 readthrough); PAK1 (p21 (RAC1) activated kinase 1); and PAK2 (p21 (RAC1) activated kinase 2). [provided by Alliance of Genome Resources, Jul 2025] |
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| Properties | |