Protein Name apoptosis inducing factor mitochondrion associated 1
Organism Danio rerio
Gene ID 373125
Gene Symbol

aifm1

UniProt Q5XFY2 (Q5XFY2_DANRE)
Relationships Total Number of functionally related compound(s) : 2
Total Number of Articles : 1
Description

apoptosis inducing factor mitochondrion associated 1

Gene Summary

Predicted to enable FAD binding activity and NAD(P)H oxidase H2O2-forming activity. Predicted to be involved in apoptotic process and mitochondrial disulfide relay system. Predicted to be located in mitochondrial envelope; nucleus; and perinuclear region of cytoplasm. Predicted to be active in mitochondrion. Is expressed in several structures, including alar plate midbrain region; digestive system; hatching gland; musculature system; and polster. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease X-linked recessive 4; X-linked deafness 5; and combined oxidative phosphorylation deficiency 6. Orthologous to human AIFM1 (apoptosis inducing factor mitochondria associated 1). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • apoptosis-inducing factor 1, mitochondrial
  • programmed cell death 8 (apoptosis-inducing factor)
  • AIF
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Properties