Protein Name dihydrolipoamide S-acetyltransferase
Organism Rattus norvegicus
Gene ID 81654
Gene Symbol

Dlat

UniProt P08461 (ODP2_RAT)
Relationships Total Number of functionally related compound(s) : 10
Total Number of Articles : 7
Description

dihydrolipoamide S-acetyltransferase

Gene Summary

Enables dihydrolipoyllysine-residue acetyltransferase activity. Involved in acetyl-CoA biosynthetic process from pyruvate and sleep. Located in mitochondrion. Part of pyruvate dehydrogenase complex. Human ortholog(s) of this gene implicated in pyruvate decarboxylase deficiency. Orthologous to human DLAT (dihydrolipoamide S-acetyltransferase). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial
  • 70 kDa mitochondrial autoantigen of primary biliary cirrhosis
  • E2
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Properties