| Protein Name | neuroligin 3 |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 171297 |
| Gene Symbol | Nlgn3 |
| UniProt | Q62889 (NLGN3_RAT), F1LPZ8 (F1LPZ8_RAT), D3ZDC0 (D3ZDC0_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
3
Total Number of Articles : 3 |
Description |
neuroligin 3 |
| Gene Summary |
Enables cell adhesion molecule binding activity; neurexin family protein binding activity; and signaling receptor activity. Involved in several processes, including inhibitory postsynaptic potential; neuron cell-cell adhesion; and synapse assembly. Acts upstream of or within synapse organization. Located in several cellular components, including excitatory synapse; inhibitory synapse; and postsynaptic membrane. Is active in GABA-ergic synapse; glutamatergic synapse; and postsynaptic specialization membrane. Used to study autism spectrum disorder. Biomarker of sciatic neuropathy. Human ortholog(s) of this gene implicated in autistic disorder. Orthologous to human NLGN3 (neuroligin 3). [provided by Alliance of Genome Resources, Jul 2025] |
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| Properties | |