Protein Name zinc finger protein of the cerebellum 1
Organism Mus musculus
Gene ID 22771
Gene Symbol


UniProt P46684 (ZIC1_MOUSE)
Relationships Total Number of functionally related compound(s) : 11
Total Number of Articles : 10

zinc finger protein of the cerebellum 1

Gene Summary

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including central nervous system development; positive regulation of protein import into nucleus; and regulation of smoothened signaling pathway. Acts upstream of or within adult walking behavior and central nervous system development. Located in cytoplasm and nucleus. Is expressed in several structures, including central nervous system; embryo mesenchyme; future brain; metanephros; and visual system. Used to study Dandy-Walker syndrome and Joubert syndrome. Human ortholog(s) of this gene implicated in Dandy-Walker syndrome and craniosynostosis. Orthologous to human ZIC1 (Zic family member 1). [provided by Alliance of Genome Resources, Apr 2022]

  • zinc finger protein ZIC 1
  • Zic family member 1 (odd-paired homolog, Drosophila)
  • odd-paired homolog
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