CPRiL

Protein Name	Protein kinase, cAMP-dependent, regulatory subunit type 2
Organism	Drosophila melanogaster
Gene ID	36041
Gene Symbol	Pka-R2
UniProt	P81900 (KAPR2_DROME)
Relationships	Total Number of functionally related compound(s) : 13 Total Number of Articles : 6
Description	Protein kinase, cAMP-dependent, regulatory subunit type 2
Gene Summary	Predicted to enable cAMP binding activity; cAMP-dependent protein kinase inhibitor activity; and protein kinase A catalytic subunit binding activity. Involved in several processes, including behavioral response to cocaine; locomotor rhythm; and response to ethanol. Located in cytoplasm. Is expressed in several structures, including adult head; adult mushroom body; gut section; synaptic neuropil domain; and synaptic neuropil subdomain. Human ortholog(s) of this gene implicated in congestive heart failure. Orthologous to several human genes including PRKAR2A (protein kinase cAMP-dependent type II regulatory subunit alpha). [provided by Alliance of Genome Resources, Jul 2025]
synonyms	protein kinase, cAMP-dependent, regulatory subunit type 2 CG15862-PA CG15862-PB CG15862-PD CG15862-PE Costal-1 Pka-R2-PA Pka-R2-PB Pka-R2-PD Pka-R2-PE cAMP-dependent protein kinase R2 cAMP-dependent protein kinase type II costal epaulette protein kinase A Dmel_CG15862 BcDNA:GM01761 CG15862 Cos Cos-1 Cos1 Dmel\CG15862 Epa PKA PKA R2 PKA RII PKA-R2 PKA-RII PKAR2 PKa-R2 Click to show/hide the synonyms
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