Protein Name methionine adenosyltransferase 1A
Organism Rattus norvegicus
Gene ID 25331
Gene Symbol

Mat1a

UniProt P13444 (METK1_RAT)
Relationships Total Number of functionally related compound(s) : 115
Total Number of Articles : 70
Description

methionine adenosyltransferase 1A

Gene Summary

Enables several functions, including adenyl ribonucleotide binding activity; magnesium ion binding activity; and methionine adenosyltransferase activity. Involved in S-adenosylmethionine biosynthetic process and protein-containing complex assembly. Located in nuclear matrix. Human ortholog(s) of this gene implicated in hypermethioninemia. Orthologous to human MAT1A (methionine adenosyltransferase 1A). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • S-adenosylmethionine synthase isoform type-1
  • MAT 1
  • MAT-I/III
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Properties