Protein Name ubiquitin interaction motif containing 1
Organism Homo sapiens
Gene ID 51720
Gene Symbol

UIMC1

UniProt Q96RL1 (UIMC1_HUMAN), A0A024R7R0 (A0A024R7R0_HUMAN)
Relationships Total Number of functionally related compound(s) : 20
Total Number of Articles : 27
Description

ubiquitin interaction motif containing 1

Gene Summary

This gene encodes a nuclear protein that interacts with Brca1 (breast cancer 1) in a complex to recognize and repair DNA lesions. This protein binds ubiquitinated lysine 63 of histone H2A and H2AX. This protein may also function as a repressor of transcription. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

synonyms
  • BRCA1-A complex subunit RAP80
  • receptor-associated protein 80
  • retinoid X receptor-interacting protein 110
Click to show/hide the synonyms
Properties