Protein Name ditrans,polycis-polyprenyl diphosphate synthase
Organism Saccharomyces cerevisiae S288C
Gene ID 852287
Gene Symbol

RER2

UniProt P35196 (RER2_YEAST)
Relationships Total Number of functionally related compound(s) : 9
Total Number of Articles : 14
Description

ditrans,polycis-polyprenyl diphosphate synthase

Gene Summary

Enables ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific] activity. Involved in dolichol biosynthetic process; endoplasmic reticulum to Golgi vesicle-mediated transport; and protein glycosylation. Located in endoplasmic reticulum and lipid droplet. Part of dehydrodolichyl diphosphate synthase complex. Used to study cancer. Human ortholog(s) of this gene implicated in developmental delay and seizures with or without movement abnormalities and retinitis pigmentosa 59. Orthologous to human DHDDS (dehydrodolichyl diphosphate synthase subunit). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • ditrans,polycis-polyprenyl diphosphate synthase
  • YBR002C
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Properties