| Protein Name | Janus kinase 2b |
|---|---|
| Organism | Danio rerio |
| Gene ID | 30298 |
| Gene Symbol | jak2b |
| UniProt | C0RW38 (C0RW38_DANRE) |
| Relationships |
Total Number of functionally related compound(s) :
4
Total Number of Articles : 3 |
Description |
Janus kinase 2b |
| Gene Summary |
Predicted to enable growth hormone receptor binding activity and non-membrane spanning protein tyrosine kinase activity. Predicted to be involved in cell differentiation; cell surface receptor signaling pathway; and intracellular signal transduction. Predicted to act upstream of or within protein phosphorylation. Predicted to be located in cytoskeleton and membrane. Predicted to be active in cytosol. Is expressed in several structures, including lateral line; lens; mandibular arch skeleton; pronephric duct; and solid lens vesicle. Human ortholog(s) of this gene implicated in several diseases, including gastrointestinal system cancer (multiple); hematologic cancer (multiple); hepatic vascular disease (multiple); inflammatory bowel disease (multiple); and lung non-small cell carcinoma (multiple). Orthologous to human JAK2 (Janus kinase 2). [provided by Alliance of Genome Resources, Apr 2025] |
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