| Protein Name | eukaryotic translation initiation factor 3 subunit D |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 8664 |
| Gene Symbol | EIF3D |
| UniProt | O15371 (EIF3D_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
12
Total Number of Articles : 10 |
Description |
eukaryotic translation initiation factor 3 subunit D |
| Gene Summary |
Eukaryotic translation initiation factor-3 (eIF3), the largest of the eIFs, is a multiprotein complex composed of at least ten nonidentical subunits. The complex binds to the 40S ribosome and helps maintain the 40S and 60S ribosomal subunits in a dissociated state. It is also thought to play a role in the formation of the 40S initiation complex by interacting with the ternary complex of eIF2/GTP/methionyl-tRNA, and by promoting mRNA binding. The protein encoded by this gene is the major RNA binding subunit of the eIF3 complex. [provided by RefSeq, Jul 2008] |
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| Properties | |