Protein Name nudix hydrolase 15
Organism Mus musculus
Gene ID 214254
Gene Symbol

Nudt15

UniProt Q8BG93 (NUD15_MOUSE)
Relationships Total Number of functionally related compound(s) : 8
Total Number of Articles : 6
Description

nudix hydrolase 15

Gene Summary

Enables 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity. Acts upstream of or within purine deoxyribonucleoside triphosphate catabolic process and response to reactive oxygen species. Predicted to be active in cytosol. Used to study leukopenia; neutropenia; and pancytopenia. Human ortholog(s) of this gene implicated in poor metabolism of thiopurines 2. Orthologous to human NUDT15 (nudix hydrolase 15). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • nucleotide triphosphate diphosphatase NUDT15
  • 7,8-dihydro-8-oxoguanine-triphosphatase NUDT15
  • 8-oxo-dGTPase NUDT15
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Properties