Protein Name nudix hydrolase 15
Organism Mus musculus
Gene ID 214254
Gene Symbol

Nudt15

UniProt Q8BG93 (NUD15_MOUSE)
Relationships Total Number of functionally related compound(s) : 8
Total Number of Articles : 6
Description

nudix hydrolase 15

Gene Summary

Enables 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity. Acts upstream of or within purine deoxyribonucleoside triphosphate catabolic process and response to reactive oxygen species. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in thiopurine S-methyltransferase deficiency. Orthologous to human NUDT15 (nudix hydrolase 15). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • nucleotide triphosphate diphosphatase NUDT15
  • 7,8-dihydro-8-oxoguanine-triphosphatase NUDT15
  • 8-oxo-dGTPase NUDT15
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Properties