| Protein Name | angiotensin II receptor, type 2 |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 24182 |
| Gene Symbol | Agtr2 |
| UniProt | P35351 (AGTR2_RAT), B1WBL8 (B1WBL8_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
284
Total Number of Articles : 535 |
Description |
angiotensin II receptor, type 2 |
| Gene Summary |
Enables angiotensin type II receptor activity. Involved in several processes, including cellular response to dexamethasone stimulus; positive regulation of branching involved in ureteric bud morphogenesis; and regulation of secretion. Located in perinuclear region of cytoplasm. Used to study chronic kidney disease; congenital diaphragmatic hernia; glomerulonephritis (multiple); hypertension (multiple); and meconium aspiration syndrome. Biomarker of several diseases, including asthma; congestive heart failure; glomerulosclerosis (multiple); hypertension; and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in IgA glomerulonephritis; end stage renal disease; hypoglycemia; intellectual disability; and vesicoureteral reflux. Orthologous to human AGTR2 (angiotensin II receptor type 2). [provided by Alliance of Genome Resources, Jul 2025] |
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| Properties | |