| Protein Name | cytochrome P450, family 2, subfamily j, polypeptide 5 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 13109 |
| Gene Symbol | Cyp2j5 |
| UniProt | O54749 (CP2J5_MOUSE), Q3TNC5 (Q3TNC5_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
21
Total Number of Articles : 11 |
Description |
cytochrome P450, family 2, subfamily j, polypeptide 5 |
| Gene Summary |
Predicted to enable heme binding activity; isomerase activity; and monooxygenase activity. Acts upstream of or within angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure; positive regulation of estrogen secretion; and renal tubular secretion. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in cytoplasm and intracellular membrane-bounded organelle. Is expressed in liver and metanephros. Human ortholog(s) of this gene implicated in hypertension; myocardial infarction; pulmonary hypertension; renal fibrosis; and renal hypertension. Orthologous to human CYP2J2 (cytochrome P450 family 2 subfamily J member 2). [provided by Alliance of Genome Resources, Apr 2025] |
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| Properties | |