Protein Name cannabinoid receptor 2
Organism Homo sapiens
Gene ID 1269
Gene Symbol

CNR2

UniProt P34972 (CNR2_HUMAN), A0A024RAH7 (A0A024RAH7_HUMAN)
Relationships Total Number of functionally related compound(s) : 746
Total Number of Articles : 972
Description

cannabinoid receptor 2

Gene Summary

The cannabinoid delta-9-tetrahydrocannabinol is the principal psychoactive ingredient of marijuana. The proteins encoded by this gene and the cannabinoid receptor 1 (brain) (CNR1) gene have the characteristics of a guanine nucleotide-binding protein (G-protein)-coupled receptor for cannabinoids. They inhibit adenylate cyclase activity in a dose-dependent, stereoselective, and pertussis toxin-sensitive manner. These proteins have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. The cannabinoid receptors are members of family 1 of the G-protein-coupled receptors. [provided by RefSeq, Jul 2008]

synonyms
  • cannabinoid receptor 2
  • cannabinoid receptor 2 (macrophage)
  • CB-2
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Properties