Protein Name early growth response 1
Organism Danio rerio
Gene ID 30498
Gene Symbol

egr1

UniProt P26632 (EGR1_DANRE), B3DKJ7 (B3DKJ7_DANRE)
Relationships Total Number of functionally related compound(s) : 8
Total Number of Articles : 7
Description

early growth response 1

Gene Summary

Predicted to enable several functions, including double-stranded DNA binding activity; promoter-specific chromatin binding activity; and zinc ion binding activity. Involved in retina layer formation. Acts upstream of or within embryonic retina morphogenesis in camera-type eye; embryonic viscerocranium morphogenesis; and glial cell development. Predicted to be located in cytoplasm and nucleus. Is expressed in head; heart; hindbrain neural keel; mesoderm; and nervous system. Human ortholog(s) of this gene implicated in asthma. Orthologous to human EGR1 (early growth response 1). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • early growth response protein 1
  • EGR-1
  • etID309970.14
Click to show/hide the synonyms
Properties