| Protein Name | WASP actin nucleation promoting factor |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 317371 |
| Gene Symbol | Was |
| UniProt | G3V9K5 (G3V9K5_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
5
Total Number of Articles : 5 |
Description |
WASP actin nucleation promoting factor |
| Gene Summary |
Predicted to enable SH3 domain binding activity; enzyme binding activity; and identical protein binding activity. Predicted to be involved in several processes, including Cdc42 protein signal transduction; positive regulation of nucleobase-containing compound metabolic process; and regulation of actin filament organization. Predicted to act upstream of or within several processes, including actin filament polymerization; cellular response to type II interferon; and endosomal transport. Predicted to be located in several cellular components, including actin filament; phagocytic vesicle; and site of double-strand break. Human ortholog(s) of this gene implicated in Wiskott-Aldrich syndrome; X-linked severe congenital neutropenia; and thrombocytopenia. Orthologous to human WAS (WASP actin nucleation promoting factor). [provided by Alliance of Genome Resources, Jul 2025] |
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| Properties | |