Protein Name neuropeptide Y receptor Y5
Organism Rattus norvegicus
Gene ID 25340
Gene Symbol

Npy5r

UniProt Q63634 (NPY5R_RAT)
Relationships Total Number of functionally related compound(s) : 51
Total Number of Articles : 37
Description

neuropeptide Y receptor Y5

Gene Summary

Enables pancreatic polypeptide receptor activity and peptide YY receptor activity. Involved in several processes, including generation of ovulation cycle rhythm; negative regulation of GABAergic synaptic transmission; and regulation of acute inflammatory response. Predicted to be located in membrane. Predicted to be active in several cellular components, including GABA-ergic synapse; neuron projection; and presynapse. Used to study absence epilepsy and hyperinsulinism. Biomarker of coronary restenosis; obesity; and prolactinoma. Human ortholog(s) of this gene implicated in lipid metabolism disorder and obesity. Orthologous to human NPY5R (neuropeptide Y receptor Y5). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • neuropeptide Y receptor type 5
  • NPY-Y5 receptor
  • NPY5-R
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Properties