Protein Name keratin 16
Organism Homo sapiens
Gene ID 3868
Gene Symbol


UniProt P08779 (K1C16_HUMAN)
Relationships Total Number of functionally related compound(s) : 53
Total Number of Articles : 60

keratin 16

Gene Summary

The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains and are clustered in a region of chromosome 17q12-q21. This keratin has been coexpressed with keratin 14 in a number of epithelial tissues, including esophagus, tongue, and hair follicles. Mutations in this gene are associated with type 1 pachyonychia congenita, non-epidermolytic palmoplantar keratoderma and unilateral palmoplantar verrucous nevus. [provided by RefSeq, Jul 2008]

  • keratin, type I cytoskeletal 16
  • cytokeratin 16
  • focal non-epidermolytic palmoplantar keratoderma
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