Protein Name potassium channel, voltage gated KQT-like subfamily Q, member 1 L homeolog
Organism Xenopus laevis
Gene ID 373746
Gene Symbol

kcnq1.L

UniProt P70057 (KCNQ1_XENLA), A0A1L8GJB4 (A0A1L8GJB4_XENLA)
Relationships Total Number of functionally related compound(s) : 36
Total Number of Articles : 32
Description

potassium channel, voltage gated KQT-like subfamily Q, member 1 L homeolog

Gene Summary

Predicted to enable delayed rectifier potassium channel activity; outward rectifier potassium channel activity; and phosphatidylinositol-4,5-bisphosphate binding activity. Predicted to act upstream of or within several processes, including intestinal absorption; membrane repolarization; and regulation of gastric acid secretion. Predicted to be located in basolateral plasma membrane; cytoplasm; and membrane raft. Predicted to be part of monoatomic ion channel complex. Predicted to colocalize with early endosome and endoplasmic reticulum. Is expressed in ectoderm; musculoskeletal system; nervous system; pharyngeal arch; and vestibuloauditory system. Human ortholog(s) of this gene implicated in heart conduction disease (multiple); long QT syndrome (multiple); and type 2 diabetes mellitus. Orthologous to human KCNQ1 (potassium voltage-gated channel subfamily Q member 1). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • potassium voltage-gated channel subfamily KQT member 1
  • IKs producing slow voltage-gated potassium channel subunit alpha xKvLQT1
  • KQT-like 1
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Properties