Protein Name guanylate kinase 1
Organism Homo sapiens
Gene ID 2987
Gene Symbol

GUK1

UniProt Q16774 (KGUA_HUMAN), Q6IBG8 (Q6IBG8_HUMAN), A0A024R3U5 (A0A024R3U5_HUMAN)
Relationships Total Number of functionally related compound(s) : 72
Total Number of Articles : 47
Description

guanylate kinase 1

Gene Summary

The protein encoded by this gene is an enzyme that catalyzes the transfer of a phosphate group from ATP to guanosine monophosphate (GMP) to form guanosine diphosphate (GDP). The encoded protein is thought to be a good target for cancer chemotherapy. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]

synonyms
  • guanylate kinase
  • ATP:GMP phosphotransferase
  • GMP kinase
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Properties