| Protein Name | hopscotch |
|---|---|
| Organism | Drosophila melanogaster |
| Gene ID | 32080 |
| Gene Symbol | hop |
| UniProt | Q24592 (JAK_DROME) |
| Relationships |
Total Number of functionally related compound(s) :
27
Total Number of Articles : 30 |
Description |
hopscotch |
| Gene Summary |
Enables cytokine receptor binding activity and non-membrane spanning protein tyrosine kinase activity. Involved in several processes, including locomotor rhythm; morphogenesis of an epithelium; and ovarian follicle cell development. Located in cytoplasmic side of plasma membrane and cytosol. Is expressed in adult head; adult mushroom body; organism; and testis. Used to study disease of cellular proliferation and hematologic cancer. Human ortholog(s) of this gene implicated in several diseases, including gastrointestinal system cancer (multiple); hematologic cancer (multiple); hepatic vascular disease (multiple); inflammatory bowel disease (multiple); and lung non-small cell carcinoma (multiple). Orthologous to several human genes including JAK1 (Janus kinase 1) and JAK3 (Janus kinase 3). [provided by Alliance of Genome Resources, Apr 2022] |
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| Properties | |