Protein Name sterol O-acyltransferase 1
Organism Rattus norvegicus
Gene ID 81782
Gene Symbol

Soat1

UniProt O70536 (SOAT1_RAT)
Relationships Total Number of functionally related compound(s) : 6
Total Number of Articles : 4
Description

sterol O-acyltransferase 1

Gene Summary

Enables sterol O-acyltransferase activity. Predicted to be involved in several processes, including cholesterol efflux; cholesterol homeostasis; and macrophage derived foam cell differentiation. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be active in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in Chagas disease. Orthologous to human SOAT1 (sterol O-acyltransferase 1). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • sterol O-acyltransferase 1
  • acyl-coenzyme A:cholesterol acyltransferase 1
  • cholesterol acyltransferase 1
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Properties