Protein Name alkB homolog 1, histone H2A dioxygenase
Organism Homo sapiens
Gene ID 8846
Gene Symbol

ALKBH1

UniProt Q13686 (ALKB1_HUMAN), Q5XKL0 (Q5XKL0_HUMAN)
Relationships Total Number of functionally related compound(s) : 243
Total Number of Articles : 284
Description

alkB homolog 1, histone H2A dioxygenase

Gene Summary

This gene encodes a homolog to the E. coli alkB gene product. The E. coli alkB protein is part of the adaptive response mechanism of DNA alkylation damage repair. It is involved in damage reversal by oxidative demethylation of 1-methyladenine and 3-methylcytosine. [provided by RefSeq, Jul 2008]

synonyms
  • nucleic acid dioxygenase ALKBH1
  • DNA 6mA demethylase
  • DNA N6-methyl adenine demethylase ALKBH1
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Properties