Protein Name tousled like kinase 2
Organism Homo sapiens
Gene ID 11011
Gene Symbol

TLK2

UniProt Q86UE8 (TLK2_HUMAN), J3QLK5 (J3QLK5_HUMAN), B4DUC2 (B4DUC2_HUMAN)
Relationships Total Number of functionally related compound(s) : 7
Total Number of Articles : 5
Description

tousled like kinase 2

Gene Summary

This gene encodes a nuclear serine/threonine kinase that was first identified in Arabidopsis. The encoded protein is thought to function in the regulation of chromatin assembly in the S phase of the cell cycle by regulating the levels of a histone H3/H4 chaperone. This protein is associated with double-strand break repair of DNA damage caused by radiation. Pseudogenes of this gene are present on chromosomes 10 and 17. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

synonyms
  • serine/threonine-protein kinase tousled-like 2
  • HsHPK
  • MRD57
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Properties