Protein Name solute carrier family 8 member A1
Organism Rattus norvegicus
Gene ID 29715
Gene Symbol

Slc8a1

UniProt Q01728 (NAC1_RAT), M0R3V7 (M0R3V7_RAT)
Relationships Total Number of functionally related compound(s) : 288
Total Number of Articles : 322
Description

solute carrier family 8 member A1

Gene Summary

Enables calcium:sodium antiporter activity. Involved in several processes, including cellular response to cAMP; metal ion transport; and regulation of heart contraction. Located in several cellular components, including T-tubule; Z disc; and dendrite. Is active in postsynaptic membrane. Used to study brain ischemia. Biomarker of brain ischemia; congestive heart failure; hypertension; and status epilepticus. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human SLC8A1 (solute carrier family 8 member A1). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • sodium/calcium exchanger 1
  • Na(+)/Ca(2+)-exchange protein 1
  • Na-Ca exchanger
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Properties