| Protein Name | alpha-L-iduronidase |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 3425 |
| Gene Symbol | IDUA |
| UniProt | P35475 (IDUA_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
149
Total Number of Articles : 169 |
Description |
alpha-L-iduronidase |
| Gene Summary |
This gene encodes an enzyme that hydrolyzes the terminal alpha-L-iduronic acid residues of two glycosaminoglycans, dermatan sulfate and heparan sulfate. This hydrolysis is required for the lysosomal degradation of these glycosaminoglycans. Mutations in this gene that result in enzymatic deficiency lead to the autosomal recessive disease mucopolysaccharidosis type I (MPS I). [provided by RefSeq, Jul 2008] |
| synonyms |
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| Properties | |