Protein Name RAS protein-specific guanine nucleotide-releasing factor 1
Organism Mus musculus
Gene ID 19417
Gene Symbol


UniProt P27671 (RGRF1_MOUSE), B2RS27 (B2RS27_MOUSE), Q9QZR7 (Q9QZR7_MOUSE)
Relationships Total Number of functionally related compound(s) : 42
Total Number of Articles : 51

RAS protein-specific guanine nucleotide-releasing factor 1

Gene Summary

Enables glutamate receptor binding activity. Involved in activation of GTPase activity; neuron projection development; and regulation of Rac protein signal transduction. Acts upstream of or within cell population proliferation; regulation of NMDA receptor activity; and regulation of neuronal synaptic plasticity. Located in cytosol and growth cone. Is expressed in several structures, including alimentary system; genitourinary system; musculoskeletal system; nervous system; and sensory organ. Orthologous to human RASGRF1 (Ras protein specific guanine nucleotide releasing factor 1). [provided by Alliance of Genome Resources, Apr 2022]

  • ras-specific guanine nucleotide-releasing factor 1
  • Ras guanine release factor beta
  • ras-specific nucleotide exchange factor CDC25
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