Protein Name | solute carrier family 2 member 4 |
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Organism | Rattus norvegicus |
Gene ID | 25139 |
Gene Symbol | Slc2a4 |
UniProt | P19357 (GLUT4_RAT) |
Relationships |
Total Number of functionally related compound(s) :
548
Total Number of Articles : 1045 |
Description |
solute carrier family 2 member 4 |
Gene Summary |
Enables D-glucose uniporter activity. Involved in several processes, including cellular response to hypoxia; glucose import in response to insulin stimulus; and regulation of synaptic vesicle budding from presynaptic endocytic zone membrane. Acts upstream of or within with a positive effect on long-term memory. Acts upstream of or within with a negative effect on short-term memory. Acts upstream of or within learning or memory and positive regulation of brain-derived neurotrophic factor receptor signaling pathway. Located in several cellular components, including T-tubule; clathrin-coated pit; and cytoplasmic vesicle. Is active in presynapse. Biomarker of pulmonary hypertension. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human SLC2A4 (solute carrier family 2 member 4). [provided by Alliance of Genome Resources, Jun 2025] |
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