Protein Name glucose-6-phosphatase catalytic subunit 1
Organism Rattus norvegicus
Gene ID 25634
Gene Symbol


UniProt P43428 (G6PC1_RAT)
Relationships Total Number of functionally related compound(s) : 510
Total Number of Articles : 664

glucose-6-phosphatase catalytic subunit 1

Gene Summary

Enables glucose-6-phosphatase activity. Involved in several processes, including gluconeogenesis; phosphorylated carbohydrate dephosphorylation; and response to resveratrol. Located in intracellular membrane-bounded organelle. Used to study type 2 diabetes mellitus. Biomarker of fatty liver disease. Human ortholog(s) of this gene implicated in hepatocellular carcinoma. Orthologous to human G6PC1 (glucose-6-phosphatase catalytic subunit 1). [provided by Alliance of Genome Resources, Apr 2022]

  • glucose-6-phosphatase catalytic subunit 1
  • G-6-Pase
  • glucose-6-phosphatase, catalytic subunit
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