| Protein Name | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 6489 |
| Gene Symbol | ST8SIA1 |
| UniProt | Q92185 (SIA8A_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
23
Total Number of Articles : 25 |
Description |
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 |
| Gene Summary |
Gangliosides are membrane-bound glycosphingolipids containing sialic acid. Ganglioside GD3 is known to be important for cell adhesion and growth of cultured malignant cells. The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to GM3 to produce gangliosides GD3 and GT3. The encoded protein may be found in the Golgi apparatus and is a member of glycosyltransferase family 29. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2015] |
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