| Protein Name | complement C3 |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 24232 |
| Gene Symbol | C3 |
| UniProt | P01026 (CO3_RAT), M0RBF1 (M0RBF1_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
200
Total Number of Articles : 139 |
Description |
complement C3 |
| Gene Summary |
Enables lipid binding activity. Involved in several processes, including positive regulation of ERK1 and ERK2 cascade; response to estradiol; and response to steroid hormone. Located in extracellular space. Used to study glomerulonephritis; membranous glomerulonephritis; obesity; pneumonia; and pre-eclampsia. Biomarker of several diseases, including artery disease (multiple); cerebrovascular disease (multiple); eye disease (multiple); pneumocystosis; and sciatic neuropathy. Human ortholog(s) of this gene implicated in several diseases, including complement deficiency (multiple); macular degeneration (multiple); paroxysmal nocturnal hemoglobinuria; sickle cell anemia; and silicosis. Orthologous to human C3 (complement C3). [provided by Alliance of Genome Resources, Apr 2022] |
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| Properties | |