Protein Name zinc finger C3HC-type containing 1
Organism Homo sapiens
Gene ID 51530
Gene Symbol

ZC3HC1

UniProt Q86WB0 (NIPA_HUMAN)
Relationships Total Number of functionally related compound(s) : 53
Total Number of Articles : 25
Description

zinc finger C3HC-type containing 1

Gene Summary

This gene encodes an F-box-containing protein that is a component of an SCF-type E3 ubiquitin ligase complex that regulates the onset of cell division. The G2/M transition in the cell cycle requires the interaction of the proteins cyclin B1 and cyclin-dependent kinase 1. The activated ubiquitin ligase complex targets the protein cyclin B1 for degradation, preventing this transition to mitosis. [provided by RefSeq, Aug 2013]

synonyms
  • zinc finger C3HC-type protein 1
  • hematopoietic stem/progenitor cell protein 216
  • nuclear interacting partner of anaplastic lymphoma kinase (ALK)
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Properties