Protein Name Spi-C transcription factor (Spi-1/PU.1 related)
Organism Mus musculus
Gene ID 20728
Gene Symbol

Spic

UniProt Q6P3D7 (SPIC_MOUSE)
Relationships Total Number of functionally related compound(s) : 52
Total Number of Articles : 45
Description

Spi-C transcription factor (Spi-1/PU.1 related)

Gene Summary

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within blastocyst development. Predicted to be active in nucleus. Is expressed in several structures, including early conceptus; genitourinary system; hemolymphoid system; liver; and nervous system. Orthologous to human SPIC (Spi-C transcription factor). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • transcription factor Spi-C
  • pu.1-related factor
  • Prf
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Properties