Protein Name alkaline ceramidase 2
Organism Homo sapiens
Gene ID 340485
Gene Symbol

ACER2

UniProt Q5QJU3 (ACER2_HUMAN), B3KVV5 (B3KVV5_HUMAN)
Relationships Total Number of functionally related compound(s) : 13
Total Number of Articles : 10
Description

alkaline ceramidase 2

Gene Summary

The sphingolipid metabolite sphingosine-1-phosphate promotes cell proliferation and survival, whereas its precursor, sphingosine, has the opposite effect. The ceramidase ACER2 hydrolyzes very long chain ceramides to generate sphingosine (Xu et al., 2006 [PubMed 16940153]).[supplied by OMIM, Jul 2010]

synonyms
  • alkaline ceramidase 2
  • alkCDase 2
  • alkaline CDase 2
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Properties