Protein Name cholinergic receptor, nicotinic, alpha polypeptide 3
Organism Mus musculus
Gene ID 110834
Gene Symbol

Chrna3

UniProt Q8R4G9 (ACHA3_MOUSE), Q0VBK4 (Q0VBK4_MOUSE)
Relationships Total Number of functionally related compound(s) : 109
Total Number of Articles : 126
Description

cholinergic receptor, nicotinic, alpha polypeptide 3

Gene Summary

Enables acetylcholine-gated cation-selective channel activity. Acts upstream of or within several processes, including activation of transmembrane receptor protein tyrosine kinase activity; behavioral response to nicotine; and chemical synaptic transmission. Is integral component of postsynaptic specialization membrane. Part of acetylcholine-gated channel complex. Is active in cholinergic synapse. Is expressed in several structures, including central nervous system; gut; myenteric nerve plexus; paravertebral ganglion; and retina. Human ortholog(s) of this gene implicated in lung cancer. Orthologous to human CHRNA3 (cholinergic receptor nicotinic alpha 3 subunit). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • neuronal acetylcholine receptor subunit alpha-3
  • alpha 3
  • neuronal nicotinic acetylcholine receptor, alpha 3 subunit
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Properties