Protein Name general transcription factor IIH subunit 5
Organism Homo sapiens
Gene ID 404672
Gene Symbol

GTF2H5

UniProt Q6ZYL4 (TF2H5_HUMAN)
Relationships Total Number of functionally related compound(s) : 26
Total Number of Articles : 11
Description

general transcription factor IIH subunit 5

Gene Summary

This gene encodes a subunit of transcription/repair factor TFIIH, which functions in gene transcription and DNA repair. This protein stimulates ERCC3/XPB ATPase activity to trigger DNA opening during DNA repair, and is implicated in regulating cellular levels of TFIIH. Mutations in this gene result in trichothiodystrophy, complementation group A. [provided by RefSeq, Mar 2009]

synonyms
  • general transcription factor IIH subunit 5
  • TFB5 ortholog
  • TFIIH basal transcription factor complex TTD-A subunit
Click to show/hide the synonyms
Properties